Gene pool: what changes allele frequency, and how would you tell?

Year 12 Biology · Wright–Fisher model, one locus, two alleles · each generation draws 2N gametes at random from the parental pool · order: random mating → selection → gene flow → chance sampling

Population size N 20

Starting p(A) 0.50

Generations 50

Fitness w_AA 1.00

Fitness w_Aa 1.00

Fitness w_aa 1.00

Migration rate m 0.00

Source p(A) 0.5

no selection acting

seed 20260831 · batch 0

p(A) over generations

rep 1 · rep 2 · rep 3 · rep 4 · rep 5

Verdict — nothing has been run yet. Press Run 5 replicates to start five independent populations from the same settings, and watch what they do differently.

Run summary

no runs yet

N = 20 p₀ = 0.50 gens = 50 w = 1.00/1.00/1.00 m = 0.00

final p(A) —

envelope —

fixed — · lost — · still segregating —

2pq now 0.500

start 0.500

Replicate 1 · generation 0

showing all 20 of 20 individuals, drawn by pairing the 2N gametes at random

AA 5 Aa 10 aa 5

Ready. Population size 20, starting frequency of A 0.50, 50 generations, no selection and no gene flow. Press Run 5 replicates to begin.