Inflammatory Cascade Simulator

Step through the innate immune response from tissue damage to pathogen clearance

1

Tissue Damage / Infection

Mast cells detect injury and release histamine.

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2

Vasodilation & Increased Permeability

Blood vessels widen; plasma leaks into tissue causing redness, heat and swelling.

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3

Phagocyte Recruitment

Neutrophils and macrophages migrate to the site (chemotaxis).

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4

Phagocytosis & Clearance

Phagocytes engulf and destroy pathogens. Pus forms from dead cells.

Click Next Step to advance through the inflammatory cascade.