Immune Tolerance Simulator
See how the immune system distinguishes self from non-self, and what happens when it fails
Self
Self
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Treg
Tc
Self cell
Pathogen
Treg (suppressor)
Effector T cell
Normal Tolerance
Autoimmune Failure
Allergic Response
Reset
Central tolerance deletes self-reactive T cells in the thymus. Peripheral tolerance keeps surviving self-reactive cells in check.