Every day, millions of people around the world are affected by disease. But what exactly is a disease? Is it just being sick, or is there more to it? Understanding what disease means is the first step to understanding how we fight it.
Think about the last time you or someone you knew was unwell. They might have had a cold, an allergy, or something more serious.
Write down your answers before reading on:
Moving beyond "feeling sick" to a scientific definition
Disease Types
In science, disease is not just "feeling unwell." It is a condition that impairs the normal functioning of the body or mind.
Diseases can be caused by many things:
Importantly, disease is different from injury. A broken bone or a cut is damage, not disease. Disease involves some ongoing process that disrupts normal body function.
When pathogens attack and spread
Infectious diseases are caused by pathogens and can spread from one organism to another. They are also called communicable diseases.
Examples include:
Infectious diseases can spread through the air, water, direct contact, or via vectors (organisms that carry pathogens). This is why isolation, handwashing, and vaccination are so important.
When the cause is inside or environmental
Non-infectious diseases are not caused by pathogens and cannot spread from person to person. They are also called non-communicable diseases (NCDs).
Major categories include:
Non-infectious diseases are the leading cause of death worldwide. According to the World Health Organization, NCDs cause about 74% of all deaths globally.
Key differences that matter for treatment and prevention
| Feature | Infectious Disease | Non-Infectious Disease |
|---|---|---|
| Cause | Pathogen (bacteria, virus, etc.) | Genetics, lifestyle, environment |
| Spread | Can spread between organisms | Cannot spread |
| Examples | Flu, COVID-19, malaria | Diabetes, asthma, cancer |
| Prevention | Vaccination, hygiene, isolation | Healthy lifestyle, screening |
| Treatment | Antibiotics, antivirals | Lifestyle changes, medication, surgery |
Understanding whether a disease is infectious or non-infectious is crucial because it determines how we prevent and treat it. You cannot catch diabetes from someone, but you can catch influenza.
"All diseases are caused by germs." No — many diseases are non-infectious. Cancer, diabetes, asthma, and genetic disorders are not caused by germs and cannot be caught from someone else.
"If you feel sick, you must have a disease." Not always. Feeling sick can be caused by temporary conditions like hunger, tiredness, or anxiety. Disease involves a specific disruption of normal body function.
Infectious diseases in Australia: While Australia has low rates of many infectious diseases compared to developing nations, outbreaks still occur. Ross River virus (transmitted by mosquitoes) affects thousands of Australians each year, mainly in rural and regional areas. Q fever, spread from livestock, is another significant concern for agricultural workers.
Non-infectious disease burden: Cardiovascular disease is Australia's biggest killer, responsible for about 1 in 4 deaths. Type 2 diabetes affects over 1.3 million Australians and is one of the fastest-growing chronic conditions. The Australian Institute of Health and Welfare tracks these trends to guide public health policy.
Closing the Gap: Aboriginal and Torres Strait Islander Australians experience higher rates of both infectious and non-infectious diseases than non-Indigenous Australians. The Closing the Gap initiative aims to reduce these disparities through targeted health programs and community-led interventions.
1. Which of the following is an infectious disease?
2. What is the main difference between infectious and non-infectious diseases?
3. A disease caused by a microorganism that can spread from person to person is called:
4. Which of these is a non-infectious disease?
5. Why is it important to know whether a disease is infectious or non-infectious?
1. Define disease and explain the difference between infectious and non-infectious diseases. Give two examples of each. 4 MARKS
2. Explain why cardiovascular disease and malaria require completely different public health responses. Use your knowledge of disease types. 4 MARKS
3. A student claims that all serious diseases are infectious. Evaluate this statement using evidence. 4 MARKS
Go back to your Think First answer. Has your understanding changed?
C — Influenza is caused by a virus and can spread from person to person, making it an infectious disease.
B — Infectious diseases are caused by pathogens and can spread between organisms. Non-infectious diseases cannot spread.
B — An infectious disease is caused by a pathogen and can spread between organisms.
C — Type 2 diabetes is a non-infectious disease linked to lifestyle factors such as diet and exercise.
B — Knowing whether a disease is infectious determines prevention strategies (vaccination, hygiene) and treatment approaches.
Model answer: A disease is a condition that impairs the normal functioning of the body or mind. An infectious disease is caused by a pathogen (such as bacteria, viruses, fungi, or protists) and can spread from one organism to another. Examples include influenza (caused by a virus) and tuberculosis (caused by bacteria). A non-infectious disease is not caused by a pathogen and cannot spread between organisms. Examples include type 2 diabetes (linked to lifestyle factors) and asthma (linked to genetics and environment).
Model answer: Cardiovascular disease is a non-infectious disease, so public health responses focus on lifestyle interventions: promoting healthy diets, encouraging exercise, reducing smoking rates, and screening for risk factors like high blood pressure. Malaria is an infectious disease caused by a protist and spread by mosquitoes, so public health responses focus on controlling the vector (insecticide-treated bed nets, draining standing water), providing antimalarial medication, and rapid diagnosis. The fundamental difference is that malaria can spread through a population via mosquitoes, while cardiovascular disease spreads only through shared risk factors, not direct transmission.
Model answer: This statement is incorrect. Many of the most serious and deadly diseases worldwide are non-infectious. According to the World Health Organization, non-communicable diseases (cardiovascular disease, cancer, chronic respiratory diseases, and diabetes) cause approximately 74% of all deaths globally. In Australia, cardiovascular disease is the leading cause of death. While infectious diseases like COVID-19 and malaria can be devastating, non-infectious diseases are responsible for more deaths overall. Seriousness depends on the specific disease, its stage, and available treatments — not on whether it is infectious or non-infectious.
Test your knowledge of disease basics! Sort conditions into infectious and non-infectious categories in this fast-paced classification challenge.
Tick when you have finished all activities and checked your answers.